产品货号:
Z27280
中文名称:
SRGAP2抗体
英文名称:
Anti-SRGAP2 Antibody (C-term)
产品规格:
50μl
发货周期:
1~3天
产品价格:
询价
抗体名称 | Anti-SRGAP2 Antibody (C-term) |
指标别名 | ARHGAP34,FNBP2,Formin binding protein 2,KIAA0456,SRGAP2,srGAP3 |
克隆性 | Polyclonal |
检验物种 | human,mouse |
应用范围 | WB |
基因名称 | SRGAP2 |
抗体来源 | Rabbit |
抗体类型 | IgG |
免疫原 | This SRGAP2 antibody is generated from a rabbit immunized with a KLH conjugated synthetic peptide between 1040-1071amino acids from the C-terminal region of human SRGAP2. |
计算分子量 | 121kDa |
成分 | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. |
纯化方式 | This antibody is purified through a protein A column,followed by peptide affinity purification |
保存条件 | Maintain refrigerated at 2~8℃ for up to 2 weeks.For long term storage,store at -20℃ in small aliquots to prevent freeze-thaw cycles. |
背景资料 | RAC1 GTPase activating protein (GAP) that binds and deforms membranes,and regulates actin dynamics to regulate cell migration and differentiation.Plays an important role in different aspects of neuronal morphogenesis and migration mainly during development of the cerebral cortex.This includes the biogenesis of neurites,where it is required for both axons and dendrites outgrowth,and the maturation of the dendritic spines.Also stimulates the branching of the leading process and negatively regulates neuron radial migration in the cerebral cortex.Its interaction and inhibition by SRGAP2C reduces the rate of spine maturation,alters dendritic spine morphology and density and indirectly increases neuronal migration.It may have implications for cognition,learning and memory.In non-neuronal cells,it may also play a role in cell migration by regulating the formation of lamellipodia and filopodia. |
Uniprot ID | O75044 |
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